The Formation of a Crystalline Oxazolidin-5-one from (L)-Alanine and its Use as a Chiral Template in the Practical Synthesis of α-Substituted Alanine Esters

Three different protocols to synthesize oxazolidin-5-ones have been studied with the goal to develop a method to synthesize a diastereomerically pure oxazolidin-5-one. A novel method is reported that uses a dynamic crystallization-induced asymmetric transformation to isolate a single diastereomer o...

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Bibliographic Details
Main Authors: Magnus Eriksson, Elio Napolitano, Jinghua Xu, Suresh Kapadia, Denis Byrne, Laurence Nummy, Nelu Grinberg, Sherri Shen, Heewon Lee, Vittorio Farina
Format: Article
Language:deu
Published: Swiss Chemical Society 2006-09-01
Series:CHIMIA
Subjects:
Online Access:https://chimia.ch/chimia/article/view/4208