Integrative bioinformatics analysis and experimental validation of key biomarkers for risk stratification in primary biliary cholangitis

Integrative bioinformatics analysis and experimental validation of key biomarkers for risk stratification in primary biliary cholangitis

Abstract Background Primary biliary cholangitis (PBC) is an autoimmune liver disease, whose etiology is yet to be fully elucidated. Currently, ursodeoxycholic acid (UDCA) is the only first-line drug. However, 40% of PBC patients respond poorly to it and carry a potential risk of disease progression....

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Bibliographic Details
Main Authors: Siyuan Tian, Yinan Hu, Miao Zhang, Kemei Wang, Guanya Guo, Bo Li, Yulong Shang, Ying Han
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Arthritis Research & Therapy
Subjects:
Primary biliary cholangitis
GEO database
Biomarker
Bioinformatics analysis
Risk stratification
Online Access:https://doi.org/10.1186/s13075-023-03163-y

Internet

https://doi.org/10.1186/s13075-023-03163-y

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