Osteonecrosis in Adults With Acute Lymphoblastic Leukemia: An Unmet Clinical Need

Osteonecrosis is a serious complication of antileukemic therapy associated with severe pain and reduced mobility, ultimately leading to joint destruction and significant long-term morbidity. The 5-year cumulative incidence of osteonecrosis ranges from 11% to 20% in adolescents and young adults to 3%...

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Bibliographic Details
Main Authors: Michaela Kuhlen, Marina Kunstreich, Nicola Gökbuget
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000544