NGAL protects against endotoxin-induced renal tubular cell damage by suppressing apoptosis

NGAL protects against endotoxin-induced renal tubular cell damage by suppressing apoptosis

Abstract Background We sought to confirm that neutrophil gelatinase-associated lipocalin (NGAL) protects against apoptosis during endotoxemia. Methods Endotoxemia was induced in rats with lipopolysaccharide (LPS; 3.5 mg/kg) and serum creatinine (SCr), urinary NGAL (uNGAL), renal histopathology confi...

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Bibliographic Details
Main Authors: Mei Han, Ying Li, Di Wen, Maodong Liu, Yuteng Ma, Bin Cong
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Nephrology
Subjects:
Neutrophil gelatinase associated lipocalin
Acute kidney injury
Apoptosis
siRNA
Lipopolysaccharide
Online Access:http://link.springer.com/article/10.1186/s12882-018-0977-3

Internet

http://link.springer.com/article/10.1186/s12882-018-0977-3

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