Targeted Next-Generation Sequencing-Based Multiple Gene Mutation Profiling of Patients with Rectal Adenocarcinoma Receiving or Not Receiving Neoadjuvant Chemoradiotherapy

Targeted Next-Generation Sequencing-Based Multiple Gene Mutation Profiling of Patients with Rectal Adenocarcinoma Receiving or Not Receiving Neoadjuvant Chemoradiotherapy

This study investigated whether oncogenic and tumor-suppressive gene mutations are involved in the differential outcomes of patients with rectal carcinoma receiving neoadjuvant chemoradiotherapy (nCRT). Genomic DNA was obtained from formalin-fixed paraffin-embedded (FFPE) specimens of patients with...

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Bibliographic Details
Main Authors: You-Kang Chang, Hui-Hwa Tseng, Chung-Man Leung, Kuo-Cheng Lu, Kuo-Wang Tsai
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
rectal carcinoma
cancer panel
next-generation sequencing
chemoradiotherapy
Online Access:https://www.mdpi.com/1422-0067/23/18/10353

Internet

https://www.mdpi.com/1422-0067/23/18/10353

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