Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors

Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors

Inflammatory Breast Cancer (IBC) is an aggressive form of invasive breast cancer, highly metastatic, representing 2–4% of all breast cancer cases in the United States. Despite its rare nature, IBC is responsible for 7–10% of all breast cancer deaths, with a 5-year survival rate of 40%. Thus, targete...

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Bibliographic Details
Main Authors: Ginette S. Santiago-Sánchez, Ricardo Noriega-Rivera, Eliud Hernández-O’Farrill, Fatma Valiyeva, Blanca Quiñones-Diaz, Emilly S. Villodre, Bisrat G. Debeb, Andrea Rosado-Albacarys, Pablo E. Vivas-Mejía
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
lipocalin-2
LCN2
IBC
inflammatory breast cancer
siRNA
small molecule inhibitors
Online Access:https://www.mdpi.com/1422-0067/22/16/8581

Internet

https://www.mdpi.com/1422-0067/22/16/8581

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