Identification of novel human damage response proteins targeted through yeast orthology.

Identification of novel human damage response proteins targeted through yeast orthology.

Studies in Saccharomyces cerevisiae show that many proteins influence cellular survival upon exposure to DNA damaging agents. We hypothesized that human orthologs of these S. cerevisiae proteins would also be required for cellular survival after treatment with DNA damaging agents. For this purpose,...

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Bibliographic Details
Main Authors: J Peter Svensson, Rebecca C Fry, Emma Wang, Luis A Somoza, Leona D Samson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3353887?pdf=render

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http://europepmc.org/articles/PMC3353887?pdf=render

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