Chemokine Therapy in Cats With Experimental Renal Fibrosis and in a Kidney Disease Pilot Study

Chemokine Therapy in Cats With Experimental Renal Fibrosis and in a Kidney Disease Pilot Study

Background: Chronic tubulointerstitial fibrosis is a common final pathway leading to end stage kidney disease in cats and has no effective treatment. The use of cell-based molecules to treat kidney fibrosis may be a promising approach. The objectives were to test the effects of intra-renal chemokine...

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Bibliographic Details
Main Authors: Julie Bennington, Shannon Lankford, Renata S. Magalhaes, Douglas Shankle, Jason Fanning, Cucu Kartini, Irma Suparto, Winda Kusumawardhani, M. ArRaniri Putra, Silmi Mariya, Gopal Badlani, J. Koudy Williams
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Veterinary Science
Subjects:
chemokine CXCL12
stromal cell-derived factor (SDF)-1α
local intra-renal injection
tubulo- interstitial fibrosis
ischemia/reperfusion injury
histomorphometry of collagen fibers
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.646087/full

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https://www.frontiersin.org/articles/10.3389/fvets.2021.646087/full

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