Prenatal selective serotonin reuptake inhibitor (SSRI) exposure induces working memory and social recognition deficits by disrupting inhibitory synaptic networks in male mice

Prenatal selective serotonin reuptake inhibitor (SSRI) exposure induces working memory and social recognition deficits by disrupting inhibitory synaptic networks in male mice

Abstract Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed antidepressant drugs in pregnant women. Infants born following prenatal exposure to SSRIs have a higher risk for behavioral abnormalities, however, the underlying mechanisms remains unknown. Therefore, we examined the e...

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Bibliographic Details
Main Authors: Weonjin Yu, Yi-Chun Yen, Young-Hwan Lee, Shawn Tan, Yixin Xiao, Hidayat Lokman, Audrey Khoo Tze Ting, Hasini Ganegala, Taejoon Kwon, Won-Kyung Ho, H. Shawn Je
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Molecular Brain
Subjects:
Prenatal
Serotonin (5-HT)
Selective serotonin reuptake inhibitor (SSRI)
Fluoxetine
Working memory
Social recognition
Online Access:http://link.springer.com/article/10.1186/s13041-019-0452-5

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http://link.springer.com/article/10.1186/s13041-019-0452-5

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