A High-Throughput Screening Approach To Repurpose FDA-Approved Drugs for Bactericidal Applications against <named-content content-type="genus-species">Staphylococcus aureus</named-content> Small-Colony Variants

A High-Throughput Screening Approach To Repurpose FDA-Approved Drugs for Bactericidal Applications against <named-content content-type="genus-species">Staphylococcus aureus</named-content> Small-Colony Variants

ABSTRACT Drug repurposing offers an expedited and economical route to develop new clinical therapeutics in comparison to traditional drug development. Growth-based high-throughput screening is concomitant with drug repurposing and enables rapid identification of new therapeutic uses for investigated...

Full description

Bibliographic Details
Main Authors: Ryan P. Trombetta, Paul M. Dunman, Edward M. Schwarz, Stephen L. Kates, Hani A. Awad
Format: Article
Language:English
Published: American Society for Microbiology 2018-10-01
Series:mSphere
Subjects:
Staphylococcus aureus
small-colony variants
high-throughput screen
drug repurposing
chronic infection
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00422-18

Internet

https://journals.asm.org/doi/10.1128/mSphere.00422-18

Similar Items