cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development.

The cAMP response element binding protein 1 (Creb1) transcription factor regulates cellular gene expression in response to elevated levels of intracellular cAMP. Creb1(-/-) fetal mice are phenotypically smaller than wildtype littermates, predominantly die in utero and do not survive after birth due...

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Bibliographic Details
Main Authors: A Daniel Bird, Sharon J Flecknoe, Kheng H Tan, P Fredrik Olsson, Nisha Antony, Theo Mantamadiotis, Richard Mollard, Stuart B Hooper, Timothy J Cole
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3050929?pdf=render