DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival

DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival

Abstract Background Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the specific types of NACT. DNA methylation is an epigenetic mechanism know...

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Bibliographic Details
Main Authors: Christine Aaserød Pedersen, Maria Dung Cao, Thomas Fleischer, Morten B. Rye, Stian Knappskog, Hans Petter Eikesdal, Per Eystein Lønning, Jörg Tost, Vessela N. Kristensen, May-Britt Tessem, Guro F. Giskeødegård, Tone F. Bathen
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Breast Cancer Research
Subjects:
DNA methylation
Locally advanced breast cancer
Survival
Treatment response
Breast cancer
Neoadjuvant chemotherapy
Online Access:https://doi.org/10.1186/s13058-022-01537-9

Internet

https://doi.org/10.1186/s13058-022-01537-9

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