Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis

Protodioscin (PD) is a steroidal saponin with various pharmacological activities, including neuro-protective, anti-inflammatory, and anti-tumor activities. However, the effect of PD on human osteosarcoma (OS) cells is unclear. In this study, we found that PD significantly inhibits the growth of huma...

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Bibliographic Details
Main Authors: Chien-Feng Huang, Yi-Hsien Hsieh, Shun-Fa Yang, Chao-Hung Kuo, Pei-Han Wang, Chung-Jung Liu, Renn-Chia Lin
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/3/395