Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis

Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis

Protodioscin (PD) is a steroidal saponin with various pharmacological activities, including neuro-protective, anti-inflammatory, and anti-tumor activities. However, the effect of PD on human osteosarcoma (OS) cells is unclear. In this study, we found that PD significantly inhibits the growth of huma...

Full description

Bibliographic Details
Main Authors: Chien-Feng Huang, Yi-Hsien Hsieh, Shun-Fa Yang, Chao-Hung Kuo, Pei-Han Wang, Chung-Jung Liu, Renn-Chia Lin
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
protodioscin
human osteosarcoma cell
apoptosis
p38MAPK
mitophagy
NIX
Online Access:https://www.mdpi.com/2073-4409/12/3/395

Similar Items

Similar Items