DNA Methylation Regulates a Set of Long Non-Coding RNAs Compromising Hepatic Identity during Hepatocarcinogenesis

DNA Methylation Regulates a Set of Long Non-Coding RNAs Compromising Hepatic Identity during Hepatocarcinogenesis

Background: Long noncoding RNAs (lncRNAs) are emerging as key players in cancer, including hepatocellular carcinoma (HCC). Here we identify the mechanism implicated in the HCC inhibition of a set of lncRNAs, and their contribution to the process of hepatocarcinogenesis. Methods and Results: The top-...

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Bibliographic Details
Main Authors: Miriam Recalde, María Gárate-Rascón, José María Herranz, María Elizalde, María Azkona, Juan P. Unfried, Loreto Boix, María Reig, Bruno Sangro, Maite G. Fernández-Barrena, Puri Fortes, Matías A. Ávila, Carmen Berasain, María Arechederra
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
lncRNAs
epigenetics
DNA methylation
hepatocellular differentiation
hepatocellular carcinoma
prognosis
Online Access:https://www.mdpi.com/2072-6694/14/9/2048

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https://www.mdpi.com/2072-6694/14/9/2048

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