Targeting hypoxia-inducible factor-1alpha: A new strategy for triple-negative breast cancer therapy

Targeting hypoxia-inducible factor-1alpha: A new strategy for triple-negative breast cancer therapy

Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is highly aggressive and hypoxic compared with other subtypes. The role of hypoxia inducible factor 1α (HIF-1α) as a key hypoxic transcription factor in oncogenic processes has been extensively studied. Recently, it has been sho...

Full description

Bibliographic Details
Main Authors: Qi Liu, Chengcheng Guan, Cui Liu, Huayao Li, Jibiao Wu, Changgang Sun
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
HIF-1α
Triple-negative breast cancer
Signaling pathways
Hypoxia
TNBC progression
Combination therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222012501

Internet

http://www.sciencedirect.com/science/article/pii/S0753332222012501

Similar Items