Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages

Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages

Sphingolipid and cholesterol metabolism are closely associated at the structural, biochemical, and functional levels. Although HDL-associated sphingosine-1-phosphate (S1P) contributes to several HDL functions, and S1P signaling regulates glucose and lipid metabolism, no study has addressed the invol...

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Bibliographic Details
Main Authors: Mithila Vaidya, Julian A. Jentsch, Susann Peters, Petra Keul, Sarah Weske, Markus H. Gräler, Emil Mladenov, George Iliakis, Gerd Heusch, Bodo Levkau
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Journal of Lipid Research
Subjects:
ATP binding cassette transporter A1
apolipoprotein A-I
atherosclerosis
high density lipoprotein
reverse cholesterol transport
sphingosine-1-phosphate
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520326146

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http://www.sciencedirect.com/science/article/pii/S0022227520326146

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