Network Pharmacology–Based Prediction and Pharmacological Validation of Effects of Astragali Radix on Acetaminophen-Induced Liver Injury

Network Pharmacology–Based Prediction and Pharmacological Validation of Effects of Astragali Radix on Acetaminophen-Induced Liver Injury

Astragali Radix (AR) has been widely used in traditional Chinese medicine prescriptions for acute and chronic liver injury. However, little is known about the effects of AR on acetaminophen (APAP)-induced liver injury (ALI). In the current study, a network pharmacology–based approach was applied to...

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Bibliographic Details
Main Authors: Yuan Peng, Gerui Zhu, Yuanyuan Ma, Kai Huang, Gaofeng Chen, Chenghai Liu, Yanyan Tao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Medicine
Subjects:
Astragali Radix
network pharmacology
acetaminophen
acetaminophen-induced acute liver injury
hepatocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.697644/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.697644/full

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