Identification of a Novel Functional Non-synonymous Single Nucleotide Polymorphism in Frizzled Class Receptor 6 Gene for Involvement in Depressive Symptoms

Identification of a Novel Functional Non-synonymous Single Nucleotide Polymorphism in Frizzled Class Receptor 6 Gene for Involvement in Depressive Symptoms

Although numerous susceptibility loci for depression have been identified in recent years, their biological function and molecular mechanism remain largely unknown. By using an exome-wide association study for depressive symptoms assessed by the Center for Epidemiological Studies Depression (CES-D)...

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Bibliographic Details
Main Authors: Haijun Han, Mengxiang Xu, Li Wen, Jiali Chen, Qiang Liu, Ju Wang, Ming D. Li, Zhongli Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
depression
genetic association
rs61753730
Fzd6
CRISPR/Cas9
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.882396/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2022.882396/full

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