Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses

Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses

Relatively well conserved domains of influenza A virus (IAV) proteins are potential candidates for the development of a universal IAV vaccine. Here, Deng et al. combine two such conserved antigens (M2e and HA stalk) in a double-layered protein nanoparticle and show that it protects against divergent...

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Bibliographic Details
Main Authors: Lei Deng, Teena Mohan, Timothy Z. Chang, Gilbert X. Gonzalez, Ye Wang, Young-Man Kwon, Sang-Moo Kang, Richard W. Compans, Julie A. Champion, Bao-Zhong Wang
Format: Article
Language:English
Published: Nature Portfolio 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02725-4

Internet

https://doi.org/10.1038/s41467-017-02725-4

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