Reward system neurodynamics during menstrual pain modulated by COMT Val158Met polymorphisms

Reward system neurodynamics during menstrual pain modulated by COMT Val158Met polymorphisms

IntroductionPrimary dysmenorrhea (PDM), characterized by cyclic pain, may involve pain modulation within the reward system (RS). The Catechol-O-methyltransferase (COMT) Val158Met polymorphism, which significantly influences dopamine activity, is linked to the regulation of both acute and chronic pai...

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Main Authors: Pei-Shan Hsu, Ching-Hsiung Liu, Ching-Ju Yang, Lin-Chien Lee, Wei-Chi Li, Hsiang-Tai Chao, Ming-Wei Lin, Li-Fen Chen, Jen-Chuen Hsieh
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
primary dysmenorrhea
COMT Val158Met polymorphism
functional magnetic resonance imaging
amplitude of low-frequency fluctuation
functional connectivity
reward system
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1457602/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2024.1457602/full

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