A Segmental Approach from Molecular Profiling to Medical Imaging to Study Bicuspid Aortic Valve Aortopathy

A Segmental Approach from Molecular Profiling to Medical Imaging to Study Bicuspid Aortic Valve Aortopathy

Bicuspid aortic valve (BAV) patients develop ascending aortic (AAo) dilation. The pathogenesis of BAV aortopathy (genetic vs. haemodynamic) remains unclear. This study aims to identify regional changes around the AAo wall in BAV patients with aortopathy, integrating molecular data and clinical imagi...

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Bibliographic Details
Main Authors: Froso Sophocleous, Estefania De Garate, Maria Giulia Bigotti, Maryam Anwar, Eva Jover, Aranzazu Chamorro-Jorganes, Cha Rajakaruna, Konstantina Mitrousi, Viola De Francesco, Aileen Wilson, Serban Stoica, Andrew Parry, Umberto Benedetto, Pierpaolo Chivasso, Frances Gill, Mark C. K. Hamilton, Chiara Bucciarelli-Ducci, Massimo Caputo, Costanza Emanueli, Giovanni Biglino
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
aortic segmentation
microRNAs
proteins
wall shear stress
Online Access:https://www.mdpi.com/2073-4409/11/23/3721

Internet

https://www.mdpi.com/2073-4409/11/23/3721

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