DAT and TH expression marks human Parkinson’s disease in peripheral immune cells

DAT and TH expression marks human Parkinson’s disease in peripheral immune cells

Abstract Parkinson’s disease (PD) is marked by a loss of dopamine neurons, decreased dopamine transporter (DAT) and tyrosine hydroxylase (TH) expression. However, this validation approach cannot be used for diagnostic, drug effectiveness or investigational purposes in human patients because midbrain...

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Bibliographic Details
Main Authors: Adithya Gopinath, Phillip Mackie, Basil Hashimi, Anna Marie Buchanan, Aidan R. Smith, Rachel Bouchard, Gerry Shaw, Martin Badov, Leila Saadatpour, Aryn Gittis, Adolfo Ramirez-Zamora, Michael S. Okun, Wolfgang J. Streit, Parastoo Hashemi, Habibeh Khoshbouei
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-022-00333-8

Internet

https://doi.org/10.1038/s41531-022-00333-8

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