Inoculation of the <i>Leishmania infantum HSP70-II</i> Null Mutant Induces Long-Term Protection against <i>L. amazonensis</i> Infection in BALB/c Mice

Inoculation of the <i>Leishmania infantum HSP70-II</i> Null Mutant Induces Long-Term Protection against <i>L. amazonensis</i> Infection in BALB/c Mice

<i>Leishmania amazonensis</i> parasites are etiological agents of cutaneous leishmaniasis in the New World. BALB/c mice are highly susceptible to <i>L. amazonensis</i> challenge due to their inability to mount parasite-dependent IFN-γ-mediated responses. Here, we analyzed the...

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Bibliographic Details
Main Authors: Manuel Soto, Laura Ramírez, José Carlos Solana, Emma C. L. Cook, Elena Hernández-García, José María Requena, Salvador Iborra
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Microorganisms
Subjects:
<i>Leishmania amazonensis</i>
live vaccines
attenuated parasites
murine leishmaniasis
BALB/c mice
IFN-γ
Online Access:https://www.mdpi.com/2076-2607/9/2/363

Internet

https://www.mdpi.com/2076-2607/9/2/363

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