Evidence of Copper Nanoparticles and Poly I:C Modulating Cas9 Interaction and Cleavage of COR (Conserved Omicron RNA)

Conserved omicron RNA (COR) is a 40 base long 99.9% conserved sequence in SARS-CoV-2 Omicron variant, predicted to form a stable stem loop, the targeted cleavage of which can be an ideal next step in controlling the spread of variants. The Cas9 enzyme has been traditionally utilized for gene editing...

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Bibliographic Details
Main Authors: Lindy G. Karrer, Elza Neelima Mathew, Juliet Nava-Chavez, Abeera Bhatti, Robert K. Delong
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/5/512