Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression

Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression

Objective: The peroxisome proliferator-activated receptor α (PPARα) is a transcription factor driving target genes involved in fatty acid β-oxidation. To what extent various PPARα interacting proteins may assist its function as a transcription factor is incompletely understood. An ORFeome-wide unbia...

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Bibliographic Details
Main Authors: Sofie J. Desmet, Jonathan Thommis, Tineke Vanderhaeghen, Edmee M.F. Vandenboorn, Dorien Clarisse, Yunkun Li, Steven Timmermans, Daria Fijalkowska, Dariusz Ratman, Evelien Van Hamme, Lode De Cauwer, Bart Staels, Luc Brunsveld, Frank Peelman, Claude Libert, Jan Tavernier, Karolien De Bosscher
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Molecular Metabolism
Subjects:
Nuclear receptor
Nuclear receptor crosstalk
PPARα
ERRα
Protein–protein interaction
PGC1α
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824000693

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http://www.sciencedirect.com/science/article/pii/S2212877824000693

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