Differences in local immune cell landscape between Q fever and atherosclerotic abdominal aortic aneurysms identified by multiplex immunohistochemistry

Differences in local immune cell landscape between Q fever and atherosclerotic abdominal aortic aneurysms identified by multiplex immunohistochemistry

Background: Chronic Q fever is a zoonosis caused by the bacterium Coxiella burnetii which can manifest as infection of an abdominal aortic aneurysm (AAA). Antibiotic therapy often fails, resulting in severe morbidity and high mortality. Whereas previous studies have focused on inflammatory processes...

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Bibliographic Details
Main Authors: Kimberley RG Cortenbach, Alexander HJ Staal, Teske Schoffelen, Mark AJ Gorris, Lieke L Van der Woude, Anne FM Jansen, Paul Poyck, Robert Jan Van Suylen, Peter C Wever, Chantal P Bleeker-Rovers, Mangala Srinivas, Konnie M Hebeda, Marcel van Deuren, Jos W Van der Meer, Jolanda M De Vries, Roland RJ Van Kimmenade
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
aortic aneurysm
inflammation
Q fever
multiplex immunohistochemistry
Online Access:https://elifesciences.org/articles/72486

Internet

https://elifesciences.org/articles/72486

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