Sulfur metabolic response in macrophage limits excessive inflammatory response by creating a negative feedback loop

Sulfur metabolic response in macrophage limits excessive inflammatory response by creating a negative feedback loop

The excessive inflammatory response of macrophages plays a vital role in the pathogenesis of various diseases. The dynamic metabolic alterations in macrophages, including amino acid metabolism, are known to orchestrate their inflammatory phenotype. To explore a new metabolic pathway that regulates t...

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Bibliographic Details
Main Authors: Haruna Takeda, Shohei Murakami, Zun Liu, Tomohiro Sawa, Masatomo Takahashi, Yoshihiro Izumi, Takeshi Bamba, Hideyo Sato, Takaaki Akaike, Hiroki Sekine, Hozumi Motohashi
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Redox Biology
Subjects:
Macrophage
Cysteine
xCT
Inflammation
Persulfide
LPS
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723002355

Internet

http://www.sciencedirect.com/science/article/pii/S2213231723002355

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