Long Prehensile Protrusions Can Facilitate Cancer Cell Invasion through the Basement Membrane

A basic process in cancer is the breaching of basement-membrane barriers to permit tissue invasion. Cancer cells can use proteases and physical mechanisms to produce initial holes in basement membranes, but how cells squeeze through this barrier into matrix environments is not well understood. We us...

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Bibliographic Details
Main Authors: Shayan S. Nazari, Andrew D. Doyle, Christopher K. E. Bleck, Kenneth M. Yamada
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/20/2474