The RNA-binding protein QKI suppresses cancer-associated aberrant splicing.

The RNA-binding protein QKI suppresses cancer-associated aberrant splicing.

Lung cancer is the leading cause of cancer-related death worldwide. Aberrant splicing has been implicated in lung tumorigenesis. However, the functional links between splicing regulation and lung cancer are not well understood. Here we identify the RNA-binding protein QKI as a key regulator of alter...

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Bibliographic Details
Main Authors: Feng-Yang Zong, Xing Fu, Wen-Juan Wei, Ya-Ge Luo, Monika Heiner, Li-Juan Cao, Zhaoyuan Fang, Rong Fang, Daru Lu, Hongbin Ji, Jingyi Hui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3983035?pdf=render

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http://europepmc.org/articles/PMC3983035?pdf=render

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