Short hairpin RNA targeting 2B gene of coxsackievirus B3 exhibits potential antiviral effects both <it>in vitro</it> and <it>in vivo</it>

Short hairpin RNA targeting 2B gene of coxsackievirus B3 exhibits potential antiviral effects both <it>in vitro</it> and <it>in vivo</it>

<p>Abstract</p> <p>Background</p> <p>Coxsackievirus B3 is an important infectious agent of viral myocarditis, pancreatitis and aseptic meningitis, but there are no specific antiviral therapeutic reagents in clinical use. RNA interference-based technology has been develo...

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Bibliographic Details
Main Authors: Yao Hailan, Zhang Yangde, He Feng, Wang Caihong, Xiao Zonghui, Zou Jizhen, Wang Fang, Liu Zhewei
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Infectious Diseases
Subjects:
Coxsackievirus
Myocarditis
shRNA
Lentivirus vector
Online Access:http://www.biomedcentral.com/1471-2334/12/177

Internet

http://www.biomedcentral.com/1471-2334/12/177

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