Immunotherapy and tumor mutational burden in cancer patients with liver metastases: A meta and real word cohort analysis

Immunotherapy and tumor mutational burden in cancer patients with liver metastases: A meta and real word cohort analysis

BackgroundThe predictive effects of liver metastases for immune-checkpoint inhibitors (ICIs) and the relationship between tumor mutational burden (TMB) and liver metastases (LM) remain unclear.MethodsA systematic review and meta-analysis were conducted to explore the heterogeneity of ICIs efficacy b...

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Bibliographic Details
Main Authors: Rui-Yan Wu, Bi-Cheng Wang, Kun Wang, Fan Xia, Zhi-Yuan Zhang, Jue-Feng Wan, Zhen Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
immune-checkpoint inhibitors
liver metastases
tumor mutational burden (TMB)
immunotherapy
meta - analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.994276/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.994276/full

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