Itaconate promotes a wound resolving phenotype in pro-inflammatory macrophages

Pathological conditions associated with dysfunctional wound healing are characterized by impaired remodelling of extracellular matrix (ECM), increased macrophage infiltration, and chronic inflammation. Macrophages also play an important role in wound healing as they drive wound closure by secretion...

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Bibliographic Details
Main Authors: Sjors Maassen, Britt Coenen, Melina Ioannidis, Karl Harber, Pieter Grijpstra, Jan Van den Bossche, Geert van den Bogaart
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722003639