Quercetin Inhibits Hephaestin Expression and Iron Transport in Intestinal Cells: Possible Role of PI3K Pathway

Quercetin Inhibits Hephaestin Expression and Iron Transport in Intestinal Cells: Possible Role of PI3K Pathway

Previous studies demonstrated that quercetin, a polyphenolic compound, inhibits the transport of iron by down-regulation of ferroportin (FPN1), an iron export protein. We have previously demonstrated that activation of the PI3K signaling pathway by zinc stimulates the intestinal iron uptake and tran...

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Bibliographic Details
Main Authors: Hanuma Naik Ramavath, Venu Konda, Raghu Pullakhandam
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Nutrients
Subjects:
polyphenols
quercetin
Caco-2 cells
iron transporters
hephaestin
ferroportin
Online Access:https://www.mdpi.com/2072-6643/15/5/1205

Internet

https://www.mdpi.com/2072-6643/15/5/1205

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