Molecular insights into Sertoli cell function: how do metabolic disorders in childhood and adolescence affect spermatogonial fate?

Abstract Male infertility is a major public health concern globally with unknown etiology in approximately half of cases. The decline in total sperm count over the past four decades and the parallel increase in childhood obesity may suggest an association between these two conditions. Here, we revie...

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Bibliographic Details
Main Authors: Rossella Cannarella, Roberto Curto, Rosita A. Condorelli, Scott D. Lundy, Sandro La Vignera, Aldo E. Calogero
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-49765-1