Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.

The nuclear pore complex (NPC) mediates nucleo-cytoplasmic transport of macromolecules and is an obligatory point of passage and functional bottleneck in the replication of some viruses. The Human Immunodeficiency Virus (HIV) has evolved the required mechanisms for active nuclear import of its genom...

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Bibliographic Details
Main Authors: Francesca Di Nunzio, Anne Danckaert, Thomas Fricke, Patricio Perez, Juliette Fernandez, Emmanuelle Perret, Pascal Roux, Spencer Shorte, Pierre Charneau, Felipe Diaz-Griffero, Nathalie J Arhel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3457934?pdf=render

Internet

http://europepmc.org/articles/PMC3457934?pdf=render

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