Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes

SWI/SNF-family chromatin remodeling complexes, such as S. cerevisiae RSC, slide and eject nucleosomes to regulate transcription. Within nucleosomes, stiff DNA sequences confer spontaneous partial unwrapping, prompting whether and how SWI/SNF-family remodelers are specialized to remodel partially-unw...

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Bibliographic Details
Main Authors: Alisha Schlichter, Margaret M Kasten, Timothy J Parnell, Bradley R Cairns
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/58130