Alloimperatorin and its epoxide derivative exhibit in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition of cell migration

The aim of the present study was to synthesize epoxide derivative of alloimperatorin and evaluating its antitumor and apoptotic effects in acute myeloid leukemia HL-60 cells. The cytotoxic effects were demonstrated by MTT assay. Fluorescence microscopy along with flow cytometry were performed to eva...

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Bibliographic Details
Main Authors: Hong Li, Xu Chao, Chun-Ling He, Xin-Mei Wang, Man Liang, Chang-Hu Dong
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2016-01-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:https://www.banglajol.info/index.php/BJP/article/view/24575