B7-H3 expression is associated with high PD-L1 expression in clear cell renal cell carcinoma and predicts poor prognosis

B7-H3 expression is associated with high PD-L1 expression in clear cell renal cell carcinoma and predicts poor prognosis

Abstract Background Clear cell Renal cell carcinoma (ccRCC) is an immunogenic tumor. B7 family members, such as CTLA-4, PD-1, and PD-L1, are the main components of immune checkpoints that regulate various immune responses. Specifically, B7-H3 regulates T cell-mediated immune responses against cancer...

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Bibliographic Details
Main Authors: Jung Hee Lee, Yong Jun Kim, Hyun Woo Ryu, Seung Won Shin, Eun Ji Kim, So Hyun Shin, Joon Young Park, So Young Kim, Chung Su Hwang, Joo-Young Na, Dong Hoon Shin, Jee Yeon Kim, Hyun Jung Lee
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Diagnostic Pathology
Subjects:
Clear cell renal cell carcinoma
Prognosis
B7-H3
PD-L1
Online Access:https://doi.org/10.1186/s13000-023-01320-0

Internet

https://doi.org/10.1186/s13000-023-01320-0

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