Energy Metabolites and Indicative Significance of α-Ketoglutarate and α-Ketoglutaramate in Assessing the Progression of Chronic Hepatoencephalopathy

In the example of a rat model with chronic hepatoencephalopathy (HE), changes in the organ morphology of rats affect the balance of metabolites of the tricarboxylic acid (TCA) cycle and metabolites of the glutamine–glutamate (Gln-Glu) cycle, namely α-ketoglutarate (αKG) and α-ketoglutaramate (αKGM),...

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Bibliographic Details
Main Authors: Yevgeniya I. Shurubor, Andrey B. Krasnikov, Elena P. Isakova, Yulia I. Deryabina, Vladimir S. Yudin, Anton A. Keskinov, Boris F. Krasnikov
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/14/2/217