The Prognostic Relevance of Poly (ADP-Ribose) Polymerase Expression in Ovarian Cancer Tissue of Wild Type and BRCA-Mutation Carrier Patients

The Prognostic Relevance of Poly (ADP-Ribose) Polymerase Expression in Ovarian Cancer Tissue of Wild Type and BRCA-Mutation Carrier Patients

(1) Background: The mechanism of platinum resistance in ovarian cancer is not fully clarified, but the properly functioning DNA repair mechanism can counteract the effect of conventional anticancer treatment. The objective of our study was to evaluate the expression of an important DNA repair enzyme...

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Bibliographic Details
Main Authors: Szabolcs Molnár, Beáta Vida, Lívia Beke, Gábor Méhes, Róbert Póka
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Diagnostics
Subjects:
ovarian cancer
BRCA mutation
PARP expression
gynecological oncology
platinum-based chemotherapy
progression-free survival
Online Access:https://www.mdpi.com/2075-4418/11/1/144

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https://www.mdpi.com/2075-4418/11/1/144

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