Highlights in USP7 inhibitors for cancer treatment

Highlights in USP7 inhibitors for cancer treatment

Ubiquitin-specific protease 7 (USP7) is a member of one of the most largely studied families of deubiquitylating enzymes. It plays a key role modulating the levels of multiple proteins, including tumor suppressors, transcription factors, epigenetic modulators, DNA repair proteins, and regulators of...

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Bibliographic Details
Main Authors: Rita I. Oliveira, Romina A. Guedes, Jorge A. R. Salvador
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Chemistry
Subjects:
ubiquitin proteasome system
deubiquitinases
USP7
USP7 inhibitors
small molecules
cancer treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.1005727/full

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https://www.frontiersin.org/articles/10.3389/fchem.2022.1005727/full

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