ANGPTL2 promotes immune checkpoint inhibitor-related murine autoimmune myocarditis
Abstract Use of immune checkpoint inhibitors (ICIs) as cancer immunotherapy advances rapidly in the clinic. Despite their therapeutic benefits, ICIs can cause clinically significant immune-related adverse events (irAEs), including myocarditis. However, the cellular and molecular mechanisms regulatin...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-05338-4 |