The Traf2 and NcK interacting kinase inhibitor NCB-0846 suppresses seizure activity involving the decrease of GRIA1

The Traf2 and NcK interacting kinase inhibitor NCB-0846 suppresses seizure activity involving the decrease of GRIA1

Epilepsy, one of the most common neurological disorders, is characterized by spontaneous recurrent seizures. Temporal lobe epilepsy (TLE) is one of the most common medically intractable seizure disorders. Traf2-and NcK-interacting kinase (TNIK) has recently attracted attention as a critical modulati...

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Bibliographic Details
Main Authors: Min Wang, Yixue Gu, Qiubo Li, Bangzhe Feng, Xinke Lv, Hao Zhang, Qingxia Kong, Zhifang Dong, Xin Tian, Yanke Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-05-01
Series:Genes and Diseases
Subjects:
Epilepsy
NCB-0846
Rat
TLE
TNIK
Traf2-and NcK-interacting kinase
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304223002544

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http://www.sciencedirect.com/science/article/pii/S2352304223002544

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