One of the active ingredients in Paeoniae Radix Alba functions as JAK1 inhibitor in rheumatoid arthritis

Objective: We aimed to explore and verify the mechanism underlying the action of the active ingredients of Paeoniae Radix Alba (PRA) in the treatment of rheumatoid arthritis (RA).Methods: The protein targets of PRA’s six active ingredients and RA were identified. Then, the intersection of the two gr...

Full description

Bibliographic Details
Main Authors: Lu Xiao, Shudian Lin, Feng Zhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.906763/full