Lower female survival from an opportunistic infection reveals progesterone-driven sex bias in trained immunity

Lower female survival from an opportunistic infection reveals progesterone-driven sex bias in trained immunity

Summary: Immune responses differ between females and males, although such sex-based variance is incompletely understood. Observing that bacteremia of the opportunistic pathogen Burkholderia gladioli caused many more deaths of female than male mice bearing genetic deficiencies in adaptive immunity, w...

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Bibliographic Details
Main Authors: Alexander P. Earhart, Natalia G. Karasseva, Kathryn M. Storey, Benjamin Olthoff, Md Bodruzzaman Sarker, Kimberly G. Laffey, Margaret J. Lange, R. Scott Rector, Laura C. Schulz, Diana Gil, Claudia M. Neuhauser, Adam G. Schrum
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723010185

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http://www.sciencedirect.com/science/article/pii/S2211124723010185

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