Naotaifang formula attenuates OGD/R-induced inflammation and ferroptosis by regulating microglial M1/M2 polarization through BMP6/SMADs signaling pathway

Naotaifang formula attenuates OGD/R-induced inflammation and ferroptosis by regulating microglial M1/M2 polarization through BMP6/SMADs signaling pathway

Background: Cerebral ischemia-reperfusion injury (CIRI), a subsequent injury caused by thrombolytic reperfusion post ischemic stroke (IS). Naotaifang (NTF) formula, a novel traditional Chinese medicine (TCM) remedy against IS, was shown to exert beneficial effects in inhibiting inflammation and inhi...

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Bibliographic Details
Main Authors: Jun Liao, Mengzhen Wei, Jianjun Wang, Jinsong Zeng, Danhong Liu, Qiusi Du, Jinwen Ge, Zhigang Mei
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Naotaifang
BMP6/SMADs
Neuroinflammation
Ferroptosis
OGD/R
Microglia
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223012635

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http://www.sciencedirect.com/science/article/pii/S0753332223012635

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