Single-cell RNA sequencing reveals roles of unique retinal microglia types in early diabetic retinopathy

Single-cell RNA sequencing reveals roles of unique retinal microglia types in early diabetic retinopathy

Abstract Background The pathophysiological mechanisms of diabetic retinopathy (DR), a blinding disease, are intricate. DR was thought to be a microvascular disease previously. However, growing studies have indicated that the retinal microglia-induced inflammation precedes microangiopathy. The binary...

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Bibliographic Details
Main Authors: Yan Wang, Xiongyi Yang, Yuxi Zhang, Libing Hong, Zhuohang Xie, Wenmin Jiang, Lin Chen, Ke Xiong, Siyu Yang, Meiping Lin, Xi Guo, Qiumo Li, Xiaoqing Deng, Yanhui Lin, Mingzhe Cao, Guoguo Yi, Min Fu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Diabetic retinopathy
Retinal microglia
Macrophages
Inflammation
Single-cell RNA sequencing
Online Access:https://doi.org/10.1186/s13098-024-01282-3

Internet

https://doi.org/10.1186/s13098-024-01282-3

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