Development and characterization of an intra‐articular fracture mediated model of post‐traumatic osteoarthritis

Development and characterization of an intra‐articular fracture mediated model of post‐traumatic osteoarthritis

Abstract Purpose This study aimed to develop and characterize a closed intra‐articular fracture (IAF) mediated post‐traumatic osteoarthritis (PTOA) model in rats to serve as a testbed for putative disease modifying interventions. Methods Male rats were subject to a 0 Joule (J), 1 J, 3 J, or 5 J blun...

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Bibliographic Details
Main Authors: Michael S. Valerio, William A. Pace, Connor P. Dolan, Jorge B. Edwards, Naveena B. Janakiram, Benjamin K. Potter, Christopher L. Dearth, Stephen M. Goldman
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Journal of Experimental Orthopaedics
Subjects:
Animal Models
Musculoskeletal System
Trauma
Comminuted Fractures
Military Personnel
Regenerative Medicine
Online Access:https://doi.org/10.1186/s40634-023-00625-9

Internet

https://doi.org/10.1186/s40634-023-00625-9

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