Adaption of an ongoing clinical trial to quickly respond to gaps in changing international recommendations: the experience of D2EFT

Adaption of an ongoing clinical trial to quickly respond to gaps in changing international recommendations: the experience of D2EFT

A rapidly changing landscape of antiretrovirals and their procurement at scale has permitted the evaluation of new optimised second-line antiretroviral therapy (ART) in low- and middle-income countries. D2EFT is an open-label randomised controlled non-inferiority phase IIIB/IV trial in people living...

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Bibliographic Details
Main Authors: Emmanuelle Papot, Simone Jacoby, Dona Arlinda, Anchalee Avihingsanon, Iskandar Azwa, Margaret Borok, Dannae Brown, Mohamed Cissé, Sounkalo Dao, Nnakelu Eriobu, Richard Kaplan, Muhammad Karyana, Nagalingeswaran Kumarasamy, Johnnie Lee, Marcelo H. Losso, Gail V. Matthews, Leonardo Perelis, Carmen Perez-Casas, Kiat Ruxrungtham, Melynda Watkins, H. Clifford Lane, Anthony Kelleher, Matthew Law, Mark N. Polizzotto
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:HIV Research & Clinical Practice
Subjects:
mams
randomised-clinical trial
fixed-dose combinations
drug-sparing regimens
tld
hiv
Online Access:http://dx.doi.org/10.1080/25787489.2022.2103572

Internet

http://dx.doi.org/10.1080/25787489.2022.2103572

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